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Topic outline
- Welcome to Pharmaceutical engineering
Welcome to Pharmaceutical engineering
Welcome to my Pharmaceutical engineering course. It is a branch of engineering
focused on discovering, formulating, and manufacturing medication, as well as
analytical and quality control processes. It utilizes the fields of chemical
engineering, biomedical engineering, and pharmaceutical sciences. Pharmaceutical
engineers are involved in all aspects of pharmaceutical manufacturing. This
includes designing and operating machines, determining product presentation,
designing packaging labels, and more.
Course Introduction:
Pharmaceutical engineering is focused on discovering, formulating, and manufacturing medication, as well as analytical and quality control processes. It utilizes the fields of chemical engineering, biomedical engineering, and pharmaceutical sciences.
Course
Code | : BPH 422 | Course
Title | : Pharmaceutical Engineering | Program | : Bachelor
of Pharmacy (B. Pharm) | Faculty | : Faculty
of Allied Health Sciences (FAHS) |
|
|
Semester
|
: Spring
|
Year
|
: 2021
|
|
Credit
|
: 3
|
Contact
Hours
|
: 3 hrs/week
|
|
Course
Level
|
: L4T1
|
Prerequisite
|
: BPH 312, BPH 322 & BPH 412
|
Course Objectives:
This course aims to create a beginner’s knowledge and working principles of pharmaceutical processes that are observed in large scaled in pharmaceutical industries and in laboratories in smaller scales. It tries to explain the “why” question of troubleshooting and maintenance of all the machines and equipments that are used on daily basis. Students of pharmacy and specifically industrial pharmacists can achieve basics of industrial operations through this course.
Rationale:
Pharmaceutical Engineering deals with unit operations and unit processes in general for better understanding of the physics behind pharmaceutical and industrial processes. This course has different unit operations along with theoretical aspects and challenges involved in pharmaceutical plant design. It also includes construction of relevant machines associated with each different unit operation.
Instruction/Guideline for the course:
- All the students registered for this course have to enroll
in Moodle.
- Students can find all the course materials from Moodle.
- All the students have to submit the soft copy of their
"Assignment" in Moodle under assignment section created here and for
this they will be graded here.
- One discussion or feedback forum is created under each of
the chapter. Students have to give their feedback on these forum and marks will
be given for their feedback
- Any announcement regarding the class will be posted on
Moodle. So they have to keep themselves always active on Moodle.
- All the quizzes and presentation will be held on online
(Moodle) and may be few of the class will be held on face to face class and it
will be announced before the class.
- The question pattern and the syllabus for the quizzes,
midterm and final exam is given here under each of the section (quizzes,
midterm and final).
- There are Midterm and Final Examination presentation forum
under these sections where students can discuss with each other about their
midterm and final exam syllabus, any problem regarding the exam etc.
Teaching tools and Strategies:
I will implement a number of strategies so that you can leave this course with a clarified knowledge base on Pharmaceutical Technology. My teaching style would include:
- Lecture- Live
- Question and Answer- During live class as well as in forum sections
- Group discussion
- Interactive Contents and Group tasks
- Video/Image clips from the web
- Supplemental materials for deeper knowledge
Assessment Strategies
The plan of assessment can be find in the given document. To sum it up we shall have:
Sl. | Assessment Type | Number of Assessment | Marks | Total Marks |
1 | Class Quiz | 3 quiz | 10 marks each | 10 (Average of 3) |
2 | Presentation | 1 presentation | 5 | 5 |
3 | Assignment | 1 assignment | 5 | 5 |
4. | Attendance | Marks for each class attended | 5 | 5 |
4 | Mid term | 10 x 2.5 marks each question | 25 | 25 |
5 | Final Examination | 10 x 5 marks each question | 50 | 50 |
1. Coulson and Richardson’s Chemical Engineering- J. F. Richardson and J.M.Coulron and R. K. Sinott, 3 rd edition, Butterworth- Heinemann.
2. Introduction to Chemical Engineering- Walter L. Badger and J.T. Banchero, 1955, Mc Graw-Hill Education.
3. Perry’s Handbook of Chemical Engineering- Robert H. Perry & Don W. Green, Mc Graw-Hill Education.
4. Chemical Engineering Techniques- Lauer & Heckmann.
5. Elementary Engineering Drawing- N. D. Bhatt and V. M. Panchal, 43 rd edition, Charotor Publisher.
6. The theory and practice of Industrial pharmacy- Herbert A. Lieberman and Leon Lachman.
Course Teacher
SABIHA ENAM SPRIHA
B.Pharm (DU), M.Pharm(DU)
Lecturer
Department of Pharmacy
Faculty of Allied Health Sciences
Dhaka, Bangladesh
Email: sabiha.pharm@diu.edu.bd
Cell no: 01760306889
- Chapter 01: Refrigeration and Air Conditioning
Chapter 01: Refrigeration and Air Conditioning
Learning outcome of this chapter:
- Explain the basic theory, types
& uses of refrigeration, air conditioning & humidification.
- Find out problems Critical
parameters identification
- Find out best technology.
- Identify importance
Chapter Content:
Refrigeration:
- Theory of refrigeration,
- refrigeration current cycle and
equipments employed for large scale refrigeration.
Air conditioning:
- Theory of air conditioning,
- application and types,
- humidification and dehumidification,
- cooling towers.
Humidity:
- Determination methods,
- methods of increasing and decreasing
humidity,
- application of humidity control in pharmaceutical industries.
Find the course materials here
Supplemental Video
How to utilize this video:
- Watch the less and try to understand the explanations given in the video
- Make notes of the key points
- Share your queries with me in the next class
Outcome from this video:
- Learn the working principles of a humidifier & dehumidifier
- Explain the different parts of these equipment.
Submit the design of refrigerator and explain its working principle.
Did you understand all topics of my lectures?
Chapter 01: Interactive session 1
Task 1. Students with odd registration number will select option a and students with even registration number will select b.
a. Write about the mechanism of humidifier.
b. Write about the mechanism of dehumidifier.
Task 2. Write about Corona Virus vaccine preservation conditions. Justify the feasibility in the perspective of Bangladesh.
*PDF only
- Quiz 01 Informations
Quiz 01 Informations
Get ready for your first quiz of the course. The details of the quiz is given below:
Date and Time: To be announced later
Syllabus:
Chapter 01 and 02 (upto 14 February)
Question Format:
5 MCQs (1 mark each), 2 Short Questions (1 marks each) and 3 True/False (1 marks each)
Total Marks: 10
Good Luck!!
- Size Reduction and Size Separation
Size Reduction and Size Separation
Learning outcome of this chapter:
- Describe the basic idea, types,
operation procedure, techniques & uses of equipment used in size reduction
& size separation.
- Applied areas.
- Find out problems
- Critical parameters
- Identification
- Compare among equipment
- Find out best equipment.
Chapter Content:
- principles of size reduction,
- objectives of size
reduction,
- factors affecting size reduction;
- principles, laws and factors
affecting energy requirements,
- different methods of size reduction,
- study of
hammer mill, fluid energy mill and disintegrator;
- various methods and
equipment employed for size separation e. g., sieving, sedimentation,
centrifugal elutriation, microscopic methods.
Chapter 02: Size reduction & Separation Folder
Restricted Not available unless:
Find the course materials here
Chapter 02: Class recordings Lesson
Is potency of drug related to particle size? Give an example.
Chapter 02: Interactive Session
Did you understand all topics of my lectures?
Have any questions regarding any topics taught in these lessons? Feel free to submit your query.
- Drying
Drying
Learning outcome of this chapter:
- Explain the theory, types,
operation procedure & uses of machines used in drying operation.
- Identify problems during
operation
- Identify Critical parameters
- Compare among machines
- Find out best machine
Chapter Content:
- Theory of drying principles,
- equilibrium moisture content,
- rate of
drying;
- drying of dilute solutions and suspensions - drum dryer, spray dryer;
- drying of solids - convection type, tray dryer, tunnel dryer, rotary dryer,
fluidized bed dryer, vacuum dryer, oven dryer, freeze dryer, radiant heat
dryers;
- automation in drying process
Fluid bed dryer working principle :
How to utilize this video:
- Watch the less and try to understand the explanations given in the video
- Make notes of the key points
- Share your queries with me in the next class
Outcome from this video:
- Learn the working principles of fluid bed dryer.
- Explain the different parts of this dryer.
Summarize the principle of tray dryer with its advantages.
Did you understand all topics of my lectures?
Explain the working principle of drum dryer with figure.
- Mid Term Exam
Mid Term Exam
Daffodil International University
Department of Pharmacy
Midterm Examination, Spring-2021
BPH-422 Pharmaceutical Engineering
Full marks: 20 Time: 25 minutes
Instructions for the exam
MCQ
- Choose one or multiple answers according to the question.
- Only one attempt is allowed for answering.
- Quiz 02
Quiz 02
Get ready for your second quiz of the course. The details of the quiz is given below:
Date and Time: Will be announced later (last week of April) (27.04.2021)
Syllabus:
Chapter 05 (Mixing -1)
Question Format:
10 MCQs (1 mark each)
Total Marks: 10
Good Luck!!
- Mixing
Mixing
Learning outcome of this chapter:
- Explain the theory, types,
operation procedure & uses of machines used in mixing operation.
- Applied area
- Identify problems during operation
- Identify critical parameters
compare among machines
- Find out best machine
Chapter Content:
- Theory of mixing:
- solid-solid,
solid-liquid, liquid-liquid and semisolid mixing;
- study of different types of
mixers used in pharmaceuticals like planetary mixers, sigma mixers, turbo
dispensers, double cone mixers, colloid mill, triple roller mill.
Working principle of blender & roller :
1.
2.
How to utilize this video:
- Watch the less and try to understand the explanations given in the video
- Make notes of the key points
- Share your queries with me in the next class
Outcome from this video:
- Learn the working principles of double cone blender & tripple roller mill
- Explain the different types of mixers used for different dosage forms.
Why mixing is more important incase of potent low dose drugs?
(Create discussion and give feedback/reply to each others answers)
Why vortex formation is undesired in liquid mixing?
Did you understand all topics of my lectures?
- Presentation
Presentation
Prepare a presentation on Pharmaceutical Engineering topics!! The details of the presentation is given below:
Final Submission Date: Will be announced later
Topic: Prepare a 3-4 min video on principle of any mixing equipment of your choice
1. First prepare a presentation on selected topic.
2. Every student needs to submit their own presentation. The presentation portion has 5 marks.
3. Presentation topic will include the following points:
Format: Submit your presentation google drive link ( choose the option 'anyone can view' before submitting the link)
Good Luck!!
- Quiz 03
- Filtration
Filtration
Learning outcome of this chapter:
- Describe the theory, types,
operation procedure & uses of machines used in filtration.
- Applied area
- Identify problems during
operation Identify Critical parameters
- Compare among machines
- Find out best machine
Chapter Content:
- Theory and factors affecting filtration,
- Types of
filter media,
- Filter aids, and selection of filters;
- Equipment like gravity
filter, pressure filter, vacuum filters, filter press, leaf filters, continuous
rotary drum filter, edge filter, sand filter, membrane filters; centrifugal
type filters: batch, semi continuous & continuous type.
Working principle of filters:
1.
2.
How to utilize this video:
- Watch the less and try to understand the explanations given in the video
- Make notes of the key points
- Share your queries with me in the next class
Outcome from this video:
- Learn the working principles of filter press & leaf filters.
- Explain the different types of filters used for different types of products.
Did you understand all topics of my lectures?
What are the basic mechamisms involved in filtration?
- Final Examination
Final Examination
Daffodil International University
Department of Pharmacy
Final Examination, Spring-2021
BPH-422 Pharmaceutical Engineering
Full marks: 25 Time: 30 minutes
Instructions for the exam
- Total Time for this examination is 30 minutes
- Total Marks of the of this examination is 25.
- Each set of questions contains equal marks (1 Marks).
- This examination question will be made up of 25 MCQ questions.
- Student will answer all of the questions.
- Questions may include two answers
- No negative marking if you choose any two options (whether wrong or right)
- But if you choose more than 2 options in case of checkbox questions, negative marking will be done.
- Each page will contain 5 questions.