Discussion of Week-8

Discussion of Week-8

Discussion of Week-8

Number of replies: 53
In reply to First post

Re: Discussion of Week-8

by Aliza Ahmed Khan -
Differenciate Between Homolog , Ortholog,  Paralog
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Zobayda Akter -

 
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Reaz Uddin Rafi -

**Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

**Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


**Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)


In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Sifat Ul Haque -

Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Mahmudur Rahman Rifat -


Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Salma Akter -

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Marupa Akter -
the common difference between :
Homolog : get gene from parents
ortholog : Common gene comes from ancestor and  creat specialization.
paralog : creat with gene duplication but specialization are same.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md. Sabbir Hasan -

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous.

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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md Maruf Ibna Nasim Nishan -


Differenciate Between Homolog , Ortholog,  Paralog

A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication  paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be lost.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Tanvir Rahman -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Toufiq Islam Swoad -

***Homolog : A gene related to a second gene by descent from a common ancestral DNA sequence.

***Ortholog : Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor

***Paralog : Paralogs are gene copies created by a duplication event within the same genome

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Hridoy Chandra Karmakar -


Homolog:
 It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.


In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Hridoy Chandra Karmakar -


Homolog:
 It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.


In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Obaidul Islam -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Sanzida Tahsin -

Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.


In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Murad Kabir -

Differentiate Between Homolog, Ortholog, Paralog

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from gene duplication.

Homolog

Homolog is similarity due to shared ancestry between a pair of structures or genes in different taxa. A divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity. Orthologs and paralogs are subcategories of homologs.

Ortholog

Ortholog is Any of two or more homologous gene sequences found in different species related by linear descent.

Paralog

Paralog is gene copies created by a duplication event within the same genome. While orthologous genes kept the same function, paralogous genes often develop different functions due to missing selective pressure on one copy of the duplicated gene.

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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md. Zahid Hasan -

Differenciate Between Homolog , Ortholog,  Paralog

A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication  paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be lost.


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md.Muktar Ali -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Tariqul Islam -

1. A gene related to a second gene by descent from a common ancestral DNA sequence.

2. Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor

3.  Paralogs are gene copies created by a duplication event within the same genome

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Himanish Debnath.[Himu] -

Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.

Differenciate Between Homolog , Ortholog,  Paralog

A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication  paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be lost.


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md. Tamjeed Monshi -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent .

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events .


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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Shakil Ahmmed -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)



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In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Md. Al Rahat Khan -

Homolog : Describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog : same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: The Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs : same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example : Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


Tags:
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by S.M.Rashedul Islam Bhuiyan 183-15-2323 -


the difference between :
Homolog:get gene from parents
Ortholog:Common gene comes from ancestor and  creat specialization.
Paralogs:creat with gene duplication but specialization are same.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Shekh Abdullah Al Mobin -
Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Fatema Tuz Jahura Dina -

Differenciate Between Homolog , Ortholog,  Paralog

A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication  paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be lost.

In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Mohammad ullah -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Sabith Hossain -
Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.



Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Sk Taherul Islam -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by Moklasur Rahman -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.
In reply to Aliza Ahmed Khan

Re: Discussion of Week-8

by rony bhuiyan -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.


Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.

In reply to First post

Re: Discussion of Week-8

by Miah Mohammad Tamjid -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


In reply to First post

Re: Discussion of Week-8

by Shakhawat Hossain 183-15-2335 -

the common difference between :
Homolog : get gene from parents
ortholog : Common gene comes from ancestor and  creat specialization.
paralog : creat with gene duplication but specialization are same.
In reply to First post

Re: Discussion of Week-8

by Anzamul Haque Akash -


Homolog:
 It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.


Tags:
In reply to First post

Re: Discussion of Week-8

by Amit Biswas -

Homolog : A gene related to a second gene by descent from a common ancestral DNA sequence.

Ortholog : Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor

Paralog : Paralogs are gene copies created by a duplication event within the same genome

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.


In reply to First post

Re: Discussion of Week-8

by Umme Honey -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


In reply to First post

Re: Discussion of Week-8

by Tusar kumar sarder -

Homolog : describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)


In reply to First post

Re: Discussion of Week-8

by Mithon Ahamed Redoy -

Homolog 

A gene related to a second gene by descent from a common ancestral DNA sequence.

Ortholog 

Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor

 Paralog 

Paralogs are gene copies created by a duplication event within the same genome Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.

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In reply to First post

Re: Discussion of Week-8

by Ramim Hossain -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events.


Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.


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In reply to First post

Re: Discussion of Week-8

by Md.Jalal Uddin Rumi (Polok) -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


In reply to First post

Re: Discussion of Week-8

by Md. Zayed Hassan Bhuiyan -

Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.


In reply to First post

Re: Discussion of Week-8

by Masud Rana 171-15-1370 -

Homolog : A gene related to a second gene by descent from a common ancestral DNA sequence.

Ortholog : Orthologs, or orthologous genes, are genes in different species that originated by vertical descent from a single gene of the last common ancestor

Paralog : Paralogs are gene copies created by a duplication event within the same genome

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication.

In reply to First post

Re: Discussion of Week-8

by Mahfuzur Rahman -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity. Orthologs and paralogs are subcategories of homologs; they are types of homologs.

 Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

 Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)
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Re: Discussion of Week-8

by Al Jubaer Rahman -

Both orthologs and paralogs are types of homologs, that is, they denote genes that derive from the same ancestral sequence. Orthologs are corresponding genes in different lineages and are a result of speciation, whereas paralogs result from a gene duplication

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Re: Discussion of Week-8

by Arafat Hosaain -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.
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Re: Discussion of Week-8

by Anik Das -
Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.



Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.
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Re: Discussion of Week-8

by Md Shahadat Hossain -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Ortholog: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).

Example: the Cas9 endonuclease from CRISPR is found in most bacterial, and same archaea species. These Cas9 proteins come from speciation events that began with a common ancestral endonuclease.

Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)

Example: Bacteroides thetaiotaomicron is a human gut commensal bacterium that has a lot of operons dedicated to carbohydrtate metabolism. These operons are similar to each other, and most of them contain a carbohydrate transmembrane transporter protein.
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Re: Discussion of Week-8

by Md Shahadat Hossain -
A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be lost.
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Re: Discussion of Week-8

by Fahim Yusuf -
Homolog: It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity. Orthologs and paralogs are subcategories of homologs; they are types of homologs.
Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.
Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.
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Re: Discussion of Week-8

by Sheblu Khan -


Homolog:
 It describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.


Orthologs: They have the same gene/protein in different species. These are derived from a common ancestor gene through vertical descent.

Paralogs: They have the same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events.


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Re: Discussion of Week-8

by Ebrahim Siddiky -
Differenciate Between Homolog , Ortholog, Paralog

A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation ortholog or to the relationship betwen genes separated by the event of genetic duplication paralog.

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

Paralogous genes (or paralogs) are a particular class of homologous genes. They are the result of gene duplication and the gene copies resulting from the duplication are called paralogous of each other. Paralogous genes can be retained in the genome after their duplication, but some copies can also be
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Re: Discussion of Week-8

by shaddan hossen -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.
Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).



Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)
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Re: Discussion of Week-8

by Rakibul Islam -
Homolog: describes a divergent evolutionary relationship between genes and proteins based on their sequence similarity/identity.

Orthologs and paralogs are subcategories of homologs; they are types of homologs.

Orthologs: same gene/protein in different species. These are derived from a common ancestor gene through vertical descent (i.e. passed down to new organisms during speciation events).


Paralogs: same genes/proteins within the genome of a species. These are derived from a common ancestor gene through duplication events (i.e. a copy of the gene is made in the genome and evolved to have another function.)