Learning Outcomes:

a)  Enrich knowledge about Pathophysiology of heart

b)  Understand drugs of heart diseases

c)   Got idea about Nitric oxide its  Biosynthesis , control, degradation and carriage of nitric oxide, effects of nitric oxide, therapeutic use of nitric oxide.

d)    Learn Transduction mechanisms as targets of drug action, voltage sensitive ion channels–structure and function, K⁺ channels, voltage sensitive Ca⁺² channels and the pharmacology of their inhibitors, agonists at b-adrenoceptors, pharmacology of Na⁺/K⁺ ATPase and gap junctions

Course Content

a) Pathophysiology of heart

b) Drugs of heart diseases

c) Vasodilators: Nitric oxide - Biosynthesis of nitric oxide and its control, degradation and carriage of nitric oxide, effects of nitric oxide, therapeutic use of nitric oxide and nitric oxide donors, inhibition of nitric oxide, clinical conditions in which nitric oxide may play a part, etc.

d) Ion channels, exchanger and pumps: Transduction mechanisms as targets of drug action, voltage sensitive ion channels–structure and function, K⁺ channels, voltage sensitive Ca⁺² channels and the pharmacology of their inhibitors, agonists at b-adrenoceptors, pharmacology of Na⁺/K⁺ ATPase and gap junctions.