Rationale: The aim of the course is to provide the students with the knowledge of Nature of the cell membrane, passage of drugs across cell membranes, various mechanisms, factors affecting drug absorption- physicochemical, physiological and pharmaceutical, routes of drug administration. The course will also provide the students purpose of bioavailability studies, relative and absolute availability, methods for assessing bioavailability, measures of bioequivalence study and single dose bioequivalence study and relevant statistics, review of regulatory requirements for conducting bioequivalence study.