Section outline

  • Welcome to

    Pharmaceutical Biotechnology


    Biotechnology is one of the leading forefronts of technologies of the future. The interdependence of human health and new products together with the advent of molecular biology manipulations along with the information management system technologies at various levels of gene, transcript, and protein has generated a new research and industrial field for pharmaceutical sciences. Thus, new technologies and existing pharmaceutical requirements have come hand-in-hand to lead to new generations of biopharmaceuticals with improved activities and selective modes of action to combat diseases such as cancer, and other debilitating illnesses.

    Biotechnology is the use of living systems and organisms to develop or make products, or any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use. Before the development of biotechnology as an independent program, the multidisciplinary task of producing a recombinant therapeutic agent, its analysis and other related fields co-existed in various institutions. However, as the applications of this area became evident and entered into educational courses and systematic education, it became independently recognized as a program namely, Pharmaceutical Biotechnology, which could be differentiated from other fields of biotechnology such as medical, agricultural, industrial, etc. In this field, it is highly desired to, not only, design, produce and control drugs by the help of microorganisms or other biological entities, but also, to influence the healthcare system through various targeted and smart pharmaceuticals.


    • Course Details

      Course Name: Pharmaceutical Biotechnology
      Course Code: BPH 421
      Course Credit: 3
      Number of Classes: 32 (minimum)
      Semester: L4T2

      Prerequisite:

      1. Biochemistry & Molecular Biology

    • Course Instructor

      Assigned Faculty: Galib Muhammad Abrar Ishtiaque
      Initial: GMA
      Designation: Lecturer (Senior Scale), Department of Pharmacy, Daffodil International University

      Counseling Hour:
      Room No 705 (AB1), Daffodil Smart City (DSC)
      "Please find the day-to-day counselling hour on the front side of my room!"


      My Academic Background:
      • Bachelor of Pharmacy, North South University, Bangladesh
      • Master of Pharmacy in Pharmaceutical Technology & Biopharmaceutics, North South University, Bangladesh
      • European Master on Translational Cosmetic & Dermatological Sciences, Universita del Piemonte Orientale, Italy
      • Master in Biomedical Sciences, Universite de Namur, Belgium
      • EUROPIN Summer School on Drug Design, University of Vienna, Austria

      My Research Experience & Interests:
      1. Microbiology (BPharm Project)
      2. Bioinformatics (MPharm Thesis)
      3. Forced Degradation and Stability Indicating Studies of INN drugs using RP-HPLC (Ongoing)

      Get in touch with me via:
      Email: galib.ph@diu.edu.bd (emails are preferred over phone calls)
      LinkedIn: Galib Muhammad Abrar Ishtiaque
      ResearchGate: Galib Muhammad Abrar Ishtiaque
      Instagram: galibology
    • Course Rationale

      • To understand the various techniques in biotechnology and their applications in the manufacturing of biopharmaceuticals and biomedical research
      • To gain knowledge in some of the physicochemical properties, pharmacology and the formulation of commonly used biopharmaceuticals
      • To understand the principles of the mechanism of some biotechnologically derived diagnostic aids/tests

    • Course Objective

      The main objective of this course is to:

      • Introduce essential principles underlining modern biotechnology, such as recombinant DNA technology and protein science
      • Describe the composition and technology of biopharmaceutical drug production, and development and use of the gene therapy, students will expand their practical knowledge and understanding of therapeutical effects as well as of undesired side effects of biopharmaceuticals
      • Describe organization & processes in biotechnology and pharmaceutical industry for their operations and research and development
      • Explain the components of, and challenges in development of biologicals and drugs in the pharmaceutical and biotechnology industry
      • Understand the ethical consequences of the developments in biotechnology


    • Intended Learning Outcome (ILO)

      Upon completion of this course, the student will be able to:

      • Explain scientific principles for biotechnology in pharmaceutical product development
      • Describe advanced biotechnology in novel drug development
      • Describe the technologies used for recombinant protein production
      • Describe the technologies for monoclonal antibody productions and their therapeutic applications
      • Describe the mechanisms how vaccine works and approaches of novel vaccine development
      • Describe commonly used gene therapy vectors and their applications
      • Describe mechanisms of using RNA for the treatment of human diseases
      • Describe advanced technologies for genome editing and their potential application in treatment of human diseases
      • Describe advantages and challenges in applying stem cell mediated therapy
      • Describe organization & processes in biotechnology and pharmaceutical industry for their operations and research and development including regulatory issues
      • Explain challenges and opportunities in development of biologicals and drugs in the pharmaceutical and biotechnology industry

    • Course Outline

      Lecture Module 1: INTRODUCTION TO BIOTECHNOLOGY

      Lecture Module 2: RECOMBINANT DNA TECHNOLOGY AND PRODUCTION OF BIOTECH COMPOUNDS

      Lecture Module 3: FORMULATION OF BIOTECH PRODUCTS

      Lecture Module 4: DELIVERY OF PROTEINOUS DRUGS

      Lecture Module 5: GENE THERAPY


    • Course Assessment Plan

      Attendance7
      Assignment5
      Presentation8
      Quiz15
      Midterm25
      Final40
      Total100